About...
Welcome to SWEET LAB, a place where academics merges with the Sweetness of Carbohydrates.
At Sweet Lab, we explore the subtle language of Carbohydrates - Nature's most abundant and intricate and information rich biomolecules. We work on decoding the mysteries of complex molecular language of 'GLYCOMES' in the living body and translating them into tangible solutions for human health.
Sweet lab is dedicated to the frontiers of synthetic organic chemistry through Total Synthesis of Oligosaccharides. Our mission is to develop precise and efficient scalable synthetic strategies that enable to make the complex oligosaccharides accessible.
At the core of the research lies the Development of Methodologies to seek the challenges related to oligosaccharides synthesis. We develop new reactions and synthetic paradigms rooted in fundamental organic chemistry.
By synthesizing carbohydrates with exact structural similarity, we aim to decode and ultimately harness their capability in various biologically relevant applications, spanning from Material sciences, Biological Sensing to Vaccine Designing, Diagnostics and Therapeutics.
Overall, at Sweet Lab, we are an extended academic family where we Question, Discover, and Analyze together.
Explore our world, discover our approach and relish the Sweetness of 'The Sweet Lab'.
Research Focus
Total Synthesis of Biologically Relevant Oligosaccharides
Our team is primarily focus on the chemical synthesis of complex oligosaccharides related to the repeating units of the O-antigens from various bacteria that posses significant threats to humans. The linker-armed synthetic oligosaccharides are aimed at further conjugation and possible vaccine designing against the deadly pathogens
Development of Methodologies for Carbohydrate Transformations
We are exploring various organic reactions for the protecting group manipulations on carbohydrates and developing novel methodologies for stereoselective glycosylations, key to the synthetic carbohydrate chemistry.
Exploiting the multivalency, we are looking at various carbohydrate decorated dendrimers and nanoparticles for diagnostic and therapeutic applications.
Carbohydrate Materials
We are developing Carbohydrate-based small molecule gelators for various applications. Also looking at the mechanical properties of crystals that are derived from partially functionalized carbohydrate derivatives.
Fundings
